منابع مشابه
Sales for anti-angiogenic drugs
In 1971, Judah Folkman developed the concept of “anti-angiogenesis” as a potential treatment of cancer due to “the prevention of new vessel sprouts from penetrating into early tumor implant” [1]. Beginning in the 1980’s, the industry exploited the field of anti-angiogenesis for creating new therapeutic molecules in angiogenesisdependent diseases. In 2004, the first anti-angiogenic drug, bevaciz...
متن کاملReactive resistance to anti-angiogenic drugs
most types of cancers, and particularly in metastatic renal cell carcinoma, with several drugs currently approved for daily clinical practice. However, secondary resistance to this family of drugs is constantly observed, and the mechanisms of resistance remain poorly understood in patients. Recently, we demonstrated that sunitinib, a tyrosine kinase inhibitor, was able to generate resistance to...
متن کاملAnti-Angiogenic Therapeutic Drugs for Treatment of Human Cancer
One of the proposed benefits of targeted therapies is reduced toxicity and improved quality of life. The approval of a new broad family of molecularly targeted anticancer drugs represents one of the most significant recent advances in clinical oncology. The growth of solid tumors is dependent on their capacity to acquire a blood supply. Much effort has been directed towards the development of d...
متن کاملThe production and sales of anti-tuberculosis drugs in China
BACKGROUND Tuberculosis (TB) is a major infectious disease globally. Adequate and proper use of anti-TB drugs is essential for TB control. This study aims to study China's production capacity and sales situation of anti-TB drugs, and to further discuss the potential for China to contribute to global TB control. METHODS The production data of anti-TB drugs in China from 2011 to 2013 and the sa...
متن کاملThromboembolic events in patients treated with anti-angiogenic drugs.
Induction of neo-angiogenesis is a fundamental step in many pathological conditions. The therapeutic value of inhibiting angiogenesis is an interesting area of research in oncology, with vascular endothelial growth factor (VEGF) being the most suitable anti-angiogenic target. In the last decade a number of anti-VEGF drugs have demonstrated, especially in combination with standard chemotherapy, ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.17373